I realized that I would have to risk getting flamed

This isn't a flame, but I thought I'd link some specific entries in the FAQ for you. Actually, I don't think anyone ever gets flamed, they just get FAQ-linked.

Like setting up playlists;

How about How can I keep my PC and my car player in perfect synch?

how best to organize stuff on the unit

How about What is the best way to organize and listen to my music?

easiest way to use it in the car without swerving off the road

How about Do I have to use the remote, or can I do everything from the front panel? and What do all the buttons do?

any handy tips that will make my life easier.

How about How do the Tweak Order functions work?, How do I skip to the next album or the next playlist?, Why can't I figure out how to do searches on the player?, or even What are some other good tricks for using the player?

But since you just got the unit, perhaps the most important FAQ link is I just got my new player and I have many gigs of MP3s to install. Is there anything I need to keep in mind?

Give that stuff a shot. Come back when you've got more questions.