I did this for a couple of songs - but with other settings as well, and couldn't tell the difference.

Check out the info at r3mix.net - but take it with a grain of salt and make sure to read elsewhere.

That said and done, all my songs are currently encoded with slightly modified r3mix (it's a VBR preset built into LAME). Basically I remove the normalizing parameter and kick the minimum bitrate up to 112kbit (the r3mix site breaks down the preset and shows you which commands it specifies - I use those commands passed to the LAME command-line exe from Audiograbber)

Bruno