Hrmm.. Im running it at 1600x1200 32bit... etc. etc.. and Only see a glitch or two every so often. The only probem I had was that with my nvidia card and XP the menu was unreadable but was fixed with: http://www.take2games.com/index.php?p=support&id=867&product=121,3,Grand%20Theft%20Auto%203,PC,Rockstar_Games,gta3&section=issues

-Greg