As SundayJumper said, it will not work.

The music is encoded left/right, and it can only send it to the DSP as left/right. The DSP has only the left and right inputs, so there is no way for the software to send anything other than left and right to the DSP.

So if you were to wire the outputs rotated 90 degrees, you would be getting the left channel out of your front speakers, and the right channel out of your rear speakers. It would sound genuinely bad, with no stereo image, and any instruments that were panned left or right would get EQ'd strangely.