I purchased the Canon 350D and I personally like the smaller size. It is definately lighter and easier to manage for me. It cuts down in weight when it comes to lugging it around all day. My only beef with the camera is that the new black body (it comes in gray, as well) has a textured surface that scratches all too easy. Most of the camera stays scratch-free, the due to the smaller size, the area just to the right of the lens tends to get fingernail scratches and such.
All in all, I'm happy with the higher mega-pixel rate, the smaller size, the (greatly increased) boot time, the higher capacity battery, and other goodies that Canon has added.