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For the record, I have the EF 75-300mm f/4.0-5.6 IS and want the EF 70-300mm f/4.5-5.6 DO IS USM

For the cost of the latter lens, I'd imagine you'd just want to go it a step further and get the 70-200mm f/2.8 ($1500, more or less, from both Canon and Nikon, with a similar feature set of bells and whistles) plus maybe a 1.4x teleconverter. Either lens would look quite pretty on your shelf when you leave it behind because it's too heavy to lug around.

In the UK the EF 70-300mm f/4.5-5.6 DO IS USM cost £849 and it weighs 720g.

The EF 70-200mm f2.8 L IS USM and EF 1.4x II Converter combined cost £1,608 and weigh 1790g.

So the combination weighs 2.5 times the weight of the single lens and costs twice the price.

The 1.4x converter loses you one stop, which turns it into and f/4.0 lens. That would make it the same at the short end as the single lens and only one stop faster at the long end.

The deal breaker of course though is that the lens and converter are white

No doubt the 70-200 has measurably better optical quality, but I'm never likely to own one because of the size, weight, price and whiteness.