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I havn't used any of the recent prosumer all in ones recently, but the ones I have tried out have all had some of the worst ergonomics and ease of use around. You need two hands to control all the inputs a camera needs while holding it steady. Withh my D60, I never navigate menus when I'd like to be shooting something, everything has a hard button and wheel that adjusts it. The SLR form factor just works so much better than a camera with external dimensions dictated by how well it'll fit in a jacket or shirt pocket.
Hm, I find ergonomics of my Sony DSC-F828 quite satisfying. As you say, one never navigates menus when shooting: there are physical buttons, mode selector and 'jog-dial' for all functions one normally needs (with exception of ISO setting). But then, at 154x134x91 mm without lense shade it certainly does not fit even in military fatigues pocket 
I was surprised to find manual focusing on Canon 350D quite unlike good old 'photochemical' SLRs: image in the viewfinder is rather small, focusing screen is clear, without microprisms or similar focusing aids, and when one touches manual focus ring on the kit lens, the part of the lens it is monted on moves sideways quite noticeably (one can see it in the viewfinder)... 
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Dragi "Bonzi" Raos
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