I'm resurrecting this thread to point out that I may have found my GPS V replacement. The Street Pilot i2 seems to do everything the GPS V did, except it uses standard memory (Transflash, and it comes with 128MB of it), and it has USB connectivity. It also talks (Oooh! Aaah!). The best part is that the street price seems to be just a hair over $250.

It's not quite shipping yet, and I'll have to wait until it does to see if the two buttons and a wheel are really usable for UI navigation. It can be battery powered, so I can use it for geocaching in a pinch, but I'll need to hold one to see if it's really awkward. I'll also want to make sure it's not slower than the GPS V or something.

Assuming it checks out, I'll definitely get one to replace my dearly departed GPS V. If it ends up not looking good, the other good news is that the Quest is now down to around $375 or so.

(edited because miniSD and TransFlash are evidently not the same thing)