I assume these are .vbs files that are going to be run from the commandline or installers or something ?

One way to enable you to debug them is this. Start the script with the following commandline:

wscript.exe //d <path to WSH file>

This tells wscript to launch the debugger, normally VS.NET or InterDev when an error occurs.

Now insert an error are the beginning of your script, I normally just put "debug.me" as the first line...

When wscript hits the error you will be given the option to launch the debugger of you choice.

Their may be a cleaner way of doing this, but this does at least work.