Go nuts:
http://www.reallyusefulproducts.co.uk/usa/Put a zip tie through each end of the top and box lip to secure it. Nearly all their boxes are the same design, regardless of size. Anything from thimble-sized to trunk sized.
This is a typical lockable network product enclosure:
http://www.youtube.com/watch?v=DWCfffFZs_kIf you have a label printer, you can label this one "The Internet - Do not disconnect!"
http://www.eplastics.com/Plastic/Display_Cases/TLLB10X10X10BLKLots of hits searching for "lockable plexiglass enclosure" or "lockable plastic box"