Thanks for the response guys. So I guess it's not all that uncommon at all?

Something I have noticed since my first post that might be important : it's indeed a pretty big excel sheet, but when my colleague uses it on his Macbook, this kind of delay doesn't happen. Could it be that Mac is more optimized than my PC for stuff like this?
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Riocar 80gig S/N : 010101580 red
Riocar 80gig (010102106) - backup