Just to chime in, I recently added a 48 to my "10 Gig" Mk.2a. The actual drive as shipped from Empeg was a 12.0GB Travelstar, and I added the 48GB Travelstar with no trouble. The hardest part of the install was finding a 2mm jumper. I disconnected the 12GB, connected the 48GB, ran the new builder, followed by the current beta developer build, and then added the slave jumper and reinstalled the 12GB. No problems reported; all appears well, it seems to be booting from the 12GB, and as of now there's about 6GB of music on the second drive. (Though, the drive= advanced search doesn't seem to work in emplode...)
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-Zandr
Mk.IIa #010101243 currently getting a 500GB SSD. More spares in the shed.