I apply a wallboard patch by putting a piece of lath or equivalent across the inside of the hole, attaching it with screws from the front. Then screw the patch to the lath that now runs across the back of the hole. For very large holes, use two pieces of lath, one towards the top and one towards the bottom. (Or left and right, if that's easier for whatever reason.)

Then mud, sand, and paint.
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Bitt Faulk