I love mouse gestures (Right+Left click to go back, etc.) but I still use IE as my main broser since I can't stand tabbed browsing. I am starting to get used to it more, but right now Avant is used for ebay, autotrader, and other site you constantly are going back and forth through pages with. It also is great for opening sites you know will feed you a ton of pop-ups. It blocks all popups no matter what the hell it is (login prompts included).