If this matters, I have a 98 acura integra.
Yes, it does matter. Actually, that's what matters the most, more than the Rio Car itself. The Rio Car is just a source for the sound, no different than a CD player in terms of what it puts out.

So the question you're asking is a standard question: "What kind of amps and speakers should I put in my car?"... and I'm sure you'll soon find out that the answer is going to vary widely depending on who you talk to.

I recommend:

If you're going to do the install yourself, call up Crutchfield and see what they recommend for amplifier, speakers, and subwoofer for that particular car. While you're at it, get the dash install kit, harness, and master sheet to make the install work correctly.

If you're going to have the install done by a professional, then go to their shop and talk to them directly about what they think would be best.
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Tony Fabris