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As to the 8:1 bend ratio, how can that even be possible in most (at least, my) circuit panels? I only have 2" or so to go from vertical to horizontal on my wires. This doesn't seem like enough physical space for a 4-6 guage wire. Not to mention the 0 guage mains that turn in almost as little radius.

It's not so much of a problem where the wire is new. Bending a tight radius once will work but it will harden the wire and subsequent unbend/bends will cause a break from fatigue.
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Glenn