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I'm seeing posts on forums from a while ago about Logitech mice freezing OS X. I assume this is only if using the Logitech software. Does anyone have more info on this? I have a Logitech mouse hooked up, but I'm not using any driver other than what's built in to OS X.

Its the Logitech software that causes the odd problems in Leopard. It used an old version of Application Enhancer as part of its control panel software which really screws up your Mac. If you want something reliable then don't use APE...