When I built my house, I did this specically with the idea of a Sonos setup. So in every room I wanted audio I put two speakers (or 4 in large rooms) in the ceiling, more in particular these . The main benefit of these speakers, other than them sounding great, is that they are 8 Ohm speakers, meaning I could use 4 or them in certain zones by wiring them in parallel..

At first I thought of putting all the zones in one central room and simply run all the speaker wires from there. While this would have had certain benefits when it comes to possible future upgrades (all wires in one central location), I decided against it in the end and simply fitted a power socket and UTP socket in specific locations in the rooms themselves. Usually at a height of +/- 6 feet. These locations where all specifically chosen because they would get covered up by a closet in front of them in the end. That way I could simply place the zoneplayers in those closets on the top shelf and you'd hardly notice them.

The main reason I chose such a setup instead of centralized, is because Sonos makes it own mesh network by letting all the zones 'talk' to each other. This is important for eg. the reach of your remote. If all zoneplayers would be located on top of each other in one central location, the reach of the remote would surely be a lot worse than with my current setup, which has at least one zoneplayer in all corners of the house... Although I must be honest and say this point might have become moot now I'm using an iPad to control it all... oh well...