I didn't make anything remotely beautiful, but I've made a time-lapse video before. I used Premiere Elements, though. The main problem for me was that my computer, despite being decently powerful, couldn't keep up with the memory requirements for making the video. I think it crashed during the rendering. It might have been another issue, but I certainly had difficulty.

If you find a good program for this I'll definitely be interested too. Premiere is good at it, but not fantastic.
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Matt