I have a friend whom is homebound (due to her injuries, she can no longer drive) and had wandered if this type of home setup would work for her situation as well.

But if you're not going to use the player in the car, why buy a CAR PLAYER?

Why not a Rio HSX-109 or use a PC/RioReceiver combination? Or a Rio Riot? Or heck, even just a PC full of MP3s? Those are all great MP3 players systems with the ability for large amounts of storage.