To win really seriously at Scrabble, you need bingos.
My wife had one when she, rmitz and I were playing a few nights ago. She still only beat me by 10 points (226 to 216, I think) after she used her letters first and got the points for our leftover letters.
She had another chance for a bingo which I guessed and blocked.
You don't get many bingos when you have the Old McDonald tiles (EIEIEIO).
Well, it wasn't quite that bad. But I got none of the 5 or more point letters, and one 4 point letter, or something similarly sad.