The "Large fonts" setting in Windows is a really disgusting feature of the operating system which, when enabled, automatically resizes and moves around all texts, objects and windows of any program, using an AI algorithm that isn´t really that intelligent after all. It totally destroys the functionality of the intelligent resize feature of Mp3/Tag Studio anyway, so you have to turn it off for proper function of the program (and trust me, it's not just me, really big programs like e.g. 3D Studio MAX openly announce that they simply do not support this Windows setting). Even all Microsoft programs released prior to the introduction of that operating system feature are totally messed up by it too.

Sorry, you'll just have to settle with using the "-noresize" command line switch, it should make it at least usable.

And you can resize the program to any size by dragging its borders (if you aren't using the "-noresize" mode of course).