Very sad.

I wish you both the very best in this difficult time. It's rather strange to see her anger towards you cited as a way to beat depression... It's certainly hard to see a strained marriage as a good thing.

Whatever the circumstances, I hope she can find a way to address her depression, and then at some point work with you through whatever other obstacles have come between you. I also hope that when you say "permanent anger," it's not an indication that you're giving up hope.

You're both in my thoughts and prayers, for certain.