My family learned over several years and cats NOT to let them out of the house.
*Poisoned.
*Hit by a car (survived to claw his way back to the porch).
*Shot.
*and the last succumbed to Feline Leukemia.
Sad stories for undeserving cats.

Cat tips:
Spey/neuter
innoculate
keep indoors
grow planters full of grass (and for fun, catnip)
work fine, last long time.