I love the Intel NUC.

Since I am considering to upgrade my home server (Windows Server) hardware, I am finally considering the following combination:

NUC (i5, USB3, Gen 4)+ Drobo 5D connected via USB3 (+ Windows Server 2012).

OS would be in an internal mSATA drive. Drobo would be the main storage unit, hosting program files, user profiles, data, of course, websites, media servers, and more.

I am not sure how the USB3-attached Drobo would work in this context. What is your take, guys? Theoretical USB3 performance would be satisfactory, but will USB3 deliver what it promises?

Sadly, there's no NUC with both Ethernet and Thunderbolt.