Well, the difference between the existing PS and XBox controllers and the GameCube controller is that the PS and XBox controller both suck and the GameCube controller was nearly perfect. At the same time, I understand your notion of changing things up, but this looks a lot like taking a giant step backwards. Turn it sideways and it's very close to being an original NES controller.

Honestly, I find the DS innovations silly. I don't want to yell at my game system and I continue to think that a stylus for a controller is awkward. (I haven't decided if "awkward" is my new mantra or Nintendo's.) That doesn't mean that there aren't better games for it than for the PSP, though, and that's what really determines how successful a game system is.
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Bitt Faulk