For games that don't support the controller specifically, so long as they work with keyboard controls, they can work with it. Though I suppose that will only get you digital controls, not the analog found on the nubs.

Seems pretty straight forward to include support though. A developer will still have to provide a control scheme that doesn't use external controls of course.

With simple flat sides (that don't hold anything) this can be used as a straight-up wireless/untethered controller even for an iPad.