Bandwidth and throughout might be an issue, if all the drivers align and it works at all.

USB 2.0 is rated 480mbit/sec but actual is often much less than the FireWire 400mbit/sec. FireWire was designed to accommodate smooth and reliable data streaming, USB not so much.

On an old computer with a slow CPU you may or may not encounter USB throughput issues with this adapter hardware series that a faster and newer computer could overcome.