Not on my Windows PC. What annoys me most about iTunes is that it doesn't have any feedback to tell you it's noticed the click. On almost all Windows apps, you click something, the focus/selection changes, and _then_ it updates the window.

Oh, and the Windows version doesn't obey Fitt's law. Try clicking on the close button on iTunes when it's maximized. There's a single-pixel-width line across the top that does nothing.

Frankly, I could write a better piece of music management software. Oh wait. I did. Twice.